Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 20/20 | 0.69 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.51 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2515517 | 0.91 | PLK1 (0.75) | PLK1PLK3PLK2 | |
| SCHEMBL2522102 | 0.91 | PLK1 (0.69) | PLK1PLK3PLK2 | |
| SCHEMBL2519286 | 0.90 | PLK1 (0.68) | PLK1PLK3PLK2 | |
| SCHEMBL2516605 | 0.89 | PLK1 (0.67) | PLK1PLK3PLK2 | |
| SCHEMBL2525032 | 0.87 | PLK1 (0.72) | PLK1PLK3PLK2 | |
| SCHEMBL2520758 | 0.87 | PLK1 (0.69) | PLK1PLK3PLK2 | |
| SCHEMBL2515499 | 0.87 | PLK1 (0.64) | PLK1PLK3PLK2 | |
| SCHEMBL2517859 | 0.87 | PLK1 (0.72) | PLK1PLK3PLK2 | |
| SCHEMBL2521108 | 0.86 | PLK1 (0.70) | PLK1PLK3PLK2 | |
| SCHEMBL2516361 | 0.86 | PLK1 (0.70) | PLK1PLK3PLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1813613-B1 | NOVEL FUSED IMIDAZOLE DERIVATIVE | MSD KK (JP) | 2012-12-19 | — | — | EP | disclosed |
| EP-1813613-A1 | NOVEL FUSED IMIDAZOLE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-08-01 | — | — | EP | disclosed |