Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.52 |
| ▸ | FABP1 | P07148 | 2/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312906 | 1.00 | KMT2A (0.59) | KMT2AAKR1C3PLA2G4BFABP1NR1H4 | |
| SCHEMBL5310865 | 0.94 | KMT2A (0.57) | KMT2AAKR1C3PLA2G4BFABP1NR1H4 | |
| SCHEMBL5310869 | 0.94 | KMT2A (0.57) | KMT2AAKR1C3PLA2G4BFABP1NR1H4 | |
| SCHEMBL14530963 | 0.91 | KMT2A (0.47) | KMT2AAKR1C3PLA2G4BFABP1NR1H4 | |
| SCHEMBL5312721 | 0.89 | KMT2A (0.56) | KMT2APLA2G4BNR1H4NPC1POLB | |
| SCHEMBL5312727 | 0.89 | KMT2A (0.56) | KMT2APLA2G4BNR1H4NPC1POLB | |
| SCHEMBL5313091 | 0.89 | PLA2G4B (0.67) | KMT2APLA2G4BNR1H4 | |
| SCHEMBL5313088 | 0.89 | PLA2G4B (0.67) | KMT2APLA2G4BNR1H4 | |
| SCHEMBL5309894 | 0.88 | PLA2G4B (0.50) | KMT2AAKR1C3PLA2G4BFABP1PPARG | |
| SCHEMBL5309885 | 0.88 | PLA2G4B (0.50) | KMT2AAKR1C3PLA2G4BFABP1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058504-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |
| WO-2007058504-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |