Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | PTGDR2 | Q9Y5Y4 | 16/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5313547 | 0.95 | KDM4E (0.55) | KDM4EALDH1A1MEN1KMT2ARXFP1 | |
| SCHEMBL5314213 | 0.93 | MEN1 (0.53) | KDM4EALDH1A1MEN1KMT2ARXFP1 | |
| SCHEMBL5309133 | 0.92 | PTGDR2 (0.48) | KDM4EALDH1A1MEN1KMT2ARXFP1 | |
| SCHEMBL19798165 | 0.90 | PTGDR2 (0.56) | KDM4EALDH1A1MEN1KMT2ARXFP1 | |
| SCHEMBL5312710 | 0.89 | MEN1 (0.58) | KDM4EALDH1A1MEN1KMT2ARXFP1 | |
| SCHEMBL5417632 | 0.87 | S1PR1 (0.53) | KDM4EALDH1A1PTGDR2CYP1A2CYP2C9 | |
| SCHEMBL5314738 | 0.87 | PTGDR2 (0.48) | KDM4EALDH1A1MEN1KMT2ARXFP1 | |
| SCHEMBL5309893 | 0.85 | PTGDR2 (0.47) | KDM4EALDH1A1MEN1KMT2ARXFP1 | |
| SCHEMBL5311836 | 0.84 | PTGDR2 (0.49) | KDM4EALDH1A1MEN1KMT2ARXFP1 | |
| SCHEMBL5311506 | 0.83 | PTGDR2 (0.56) | KDM4EALDH1A1MEN1KMT2APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007051133-A2 | SUBSTITUTED THIAZOLES AND THEIR USE | MUTSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-05-03 | — | — | WO | claimed |
| WO-2007051133-A2 | SUBSTITUTED THIAZOLES AND THEIR USE | MUTSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-05-03 | — | — | WO | disclosed |
| WO-2007051133-A2 | SUBSTITUTED THIAZOLES AND THEIR USE | MUTSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-05-03 | — | — | WO | disclosed |