SCHEMBL5312924

SCHEMBL5312924

CC(C)N(CCN1CCOCC1)C(=O)C(C)N1CCC(N(CC(N)=O)S(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5226614 1.00 F10 (1.00) F10
SCHEMBL5223932 0.93 F10 (1.00) F10
Formic Acid SCHEMBL5224438 0.90 F10 (0.82) F10
Formic Acid SCHEMBL5226405 0.90 F10 (0.94) F10
Formic Acid SCHEMBL5223320 0.89 F10 (0.80) F10
SCHEMBL5223610 0.89 F10 (1.00) F10
SCHEMBL6623027 0.89 F10 (0.88) F10
Formic Acid SCHEMBL5225721 0.89 F10 (0.79) F10
Hydrochloric Acid SCHEMBL5224430 0.88 F10 (0.87) F10
SCHEMBL5225723 0.88 F10 (0.78) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1444201-B1 2-(3-SULFONYLAMINO-2-OXOPYRROLIDIN-1-YL)PROPANAMIDES AS FACTOR XA INHIBITORS GLAXO GROUP LTD (GB) 2007-09-12 EP disclosed