Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 19/20 | 0.58 |
| ▸ | NPY1R | P25929 | 11/20 | 0.58 |
| ▸ | NPY5R | Q15761 | 10/20 | 0.58 |
| ▸ | NPY2R | P49146 | 7/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30090470 | 0.95 | NPY4R (0.62) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL31257079 | 0.92 | NPY4R (0.64) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL31590213 | 0.91 | NPY4R (0.62) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL31243206 | 0.90 | NPY4R (0.62) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29391074 | 0.90 | NPY4R (0.59) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL21481072 | 0.90 | NPY4R (0.59) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30363514 | 0.87 | NPY4R (0.59) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29447211 | 0.87 | GNPAT (0.54) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30692729 | 0.87 | GNPAT (0.54) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL15092950 | 0.87 | NPY4R (0.54) | NPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025366-A1 | USE OF HISTOGRANIN AND HISTOGRANIN-LIKE COMPOUNDS AS INHIBITORS OF P2X7 RECEPTOR FUNCTION AND AS ANTI-ARTHRITIC AGENTS | BERNATCHEZ-LEMAIRE IRMA (CA) | 2007-03-08 | — | — | WO | disclosed |