Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMUR2 | Q9GZQ4 | 5/20 | 0.50 |
| ▸ | NMUR1 | Q9HB89 | 5/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.50 |
| ▸ | RAMP3 | O60896 | 6/20 | 0.49 |
| ▸ | CALCR | P30988 | 6/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | EPHA2 | P29317 | 4/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5313550 | 1.00 | NMUR2 (0.50) | NMUR2NMUR1CXCR4RAMP3CALCR | |
| SCHEMBL31031571 | 0.96 | NMUR2 (0.51) | NMUR2NMUR1CXCR4RAMP3CALCR | |
| SCHEMBL5318176 | 0.94 | CXCR4 (0.51) | NMUR2NMUR1CXCR4RAMP3CALCR | |
| SCHEMBL5318180 | 0.94 | CXCR4 (0.51) | NMUR2NMUR1CXCR4RAMP3CALCR | |
| SCHEMBL30799261 | 0.93 | NMUR2 (0.49) | NMUR2NMUR1CXCR4EPHA2 | |
| SCHEMBL31621423 | 0.93 | CAPN1 (0.52) | CXCR4RAMP3CALCRPLK1EPHA2 | |
| SCHEMBL5311906 | 0.93 | CXCR4 (0.46) | NMUR2NMUR1CXCR4RAMP3CALCR | |
| SCHEMBL5311916 | 0.93 | CXCR4 (0.46) | NMUR2NMUR1CXCR4RAMP3CALCR | |
| SCHEMBL5315506 | 0.91 | RAMP3 (0.59) | NMUR2NMUR1CXCR4RAMP3CALCR | |
| SCHEMBL5315503 | 0.91 | RAMP3 (0.59) | NMUR2NMUR1CXCR4RAMP3CALCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056047-A2 | ANTIBODIES, ASSAYS AND KITS TO QUANTITATE CARTILAGE DESTRUCTION | ARTICULAR ENGINEERING, LLC. (US) | 2007-05-18 | — | — | WO | claimed |
| US-20070099246-A1 | Antibodies, assays and kits to quantitate cartilage destruction | SANDY JOHN D | 2007-05-03 | — | — | US | claimed |
| WO-2007056047-A2 | ANTIBODIES, ASSAYS AND KITS TO QUANTITATE CARTILAGE DESTRUCTION | ARTICULAR ENGINEERING, LLC. (US) | 2007-05-18 | — | — | WO | disclosed |
| US-20070099246-A1 | Antibodies, assays and kits to quantitate cartilage destruction | SANDY JOHN D | 2007-05-03 | — | — | US | disclosed |