Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.46 |
| ▸ | RAMP3 | O60896 | 6/20 | 0.46 |
| ▸ | CALCR | P30988 | 6/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KDM5A | P29375 | 1/20 | 0.45 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | EPHA2 | P29317 | 4/20 | 0.44 |
| ▸ | F2R | P25116 | 2/20 | 0.43 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.43 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.43 |
| ▸ | NPY4R | P50391 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5313745 | 1.00 | PLK1 (0.47) | PLK1CXCR4RAMP3CALCRKDM1A | |
| SCHEMBL5311906 | 0.94 | CXCR4 (0.46) | PLK1CXCR4RAMP3CALCRKDM1A | |
| SCHEMBL5311916 | 0.94 | CXCR4 (0.46) | PLK1CXCR4RAMP3CALCRKDM1A | |
| SCHEMBL5311768 | 0.93 | KDM1A (0.46) | CXCR4RAMP3CALCRKDM1AMAOB | |
| SCHEMBL5311771 | 0.93 | KDM1A (0.46) | CXCR4RAMP3CALCRKDM1AMAOB | |
| SCHEMBL31694483 | 0.89 | NMUR2 (0.53) | PLK1CXCR4RAMP3CALCRKDM1A | |
| SCHEMBL29466786 | 0.88 | MAPK8 (0.47) | RAMP3CALCREPHA2F2RNMUR2 | |
| SCHEMBL5312908 | 0.88 | KDM1A (0.51) | RAMP3CALCRKDM1AMAOBKDM5A | |
| SCHEMBL5312915 | 0.88 | KDM1A (0.51) | RAMP3CALCRKDM1AMAOBKDM5A | |
| SCHEMBL30974022 | 0.87 | RAMP3 (0.50) | PLK1CXCR4RAMP3CALCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056047-A2 | ANTIBODIES, ASSAYS AND KITS TO QUANTITATE CARTILAGE DESTRUCTION | ARTICULAR ENGINEERING, LLC. (US) | 2007-05-18 | — | — | WO | claimed |
| US-20070099246-A1 | Antibodies, assays and kits to quantitate cartilage destruction | SANDY JOHN D | 2007-05-03 | — | — | US | claimed |
| US-20070099246-A1 | Antibodies, assays and kits to quantitate cartilage destruction | SANDY JOHN D | 2007-05-03 | — | — | US | disclosed |