Tropolone

Tropolone

SCHEMBL531387

O=c1cccccc1O.[Fe]

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DBH P09172 3/20 0.94
MMP2 P08253 1/20 0.94
HDAC4 P56524 4/20 0.56
HDAC2 Q92769 4/20 0.56
HDAC8 Q9BY41 4/20 0.56
KDM4E B2RXH2 4/20 0.54
TDP1 Q9NUW8 4/20 0.54
MAPT P10636 3/20 0.54
MEN1 O00255 1/20 0.54
HSP90AA1 P07900 1/20 0.54
MAPK1 P28482 1/20 0.54
KMT2A Q03164 1/20 0.54
CA2 P00918 5/20 0.50
ALDH1A1 P00352 4/20 0.50
HPGD P15428 4/20 0.50
CA12 O43570 4/20 0.50
CA14 Q9ULX7 4/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
CA4 P22748 3/20 0.50
HSD17B10 Q99714 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tropolone SCHEMBL42739 0.97
Tropolone SCHEMBL29029471 0.94 DBH (0.94) DBHMMP2HDAC4HDAC2HDAC8
Tropolone SCHEMBL16910519 0.94 DBH (0.94) DBHMMP2HDAC4HDAC2HDAC8
Tropolone SCHEMBL9643137 0.94 DBH (0.94) DBHMMP2HDAC4HDAC2HDAC8
Tropolone SCHEMBL9644163 0.94 DBH (0.94) DBHMMP2HDAC4HDAC2HDAC8
Tropolone SCHEMBL5969452 0.94 DBH (0.94) DBHMMP2HDAC4HDAC2HDAC8
Tropolone SCHEMBL9643338 0.94 DBH (0.94) DBHMMP2HDAC4HDAC2HDAC8
Tropolone SCHEMBL9644286 0.94 DBH (0.94) DBHMMP2HDAC4HDAC2HDAC8
Tropolone SCHEMBL9643396 0.94 DBH (0.94) DBHMMP2HDAC4HDAC2HDAC8
Tropolone SCHEMBL9644375 0.94 DBH (0.94) DBHMMP2HDAC4HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3267255-B1 LITHOGRAPHIC PRINTING ORIGINAL PLATE, METHOD FOR PRODUCING LITHOGRAPHIC PRINTING PLATE USING SAME, AND METHOD FOR PRODUCING PRINTED MATTER TORAY INDUSTRIES (JP) 2023-07-12 EP disclosed
EP-3222435-B1 METHOD FOR MANUFACTURING PRINTED MATTER TORAY INDUSTRIES (JP) 2021-11-24 EP disclosed
US-10850548-B2 Lithographic printing precursor TORAY INDUSTRIES, INC. (JP) 2020-12-01 US disclosed
US-20190143730-A1 LITHOGRAPHIC PRINTING PRECURSOR TORAY INDUSTRIES, INC. (JP) 2019-05-16 US disclosed
EP-3467587-A1 LITHOGRAPHIC PRINTING ORIGINAL PLATE Toray Industries, Inc. (JP) 2019-04-10 EP disclosed
EP-2624053-B1 DIRECT DRAWING-TYPE WATERLESS LITHOGRAPHIC PRINTING ORIGINAL PLATE TORAY INDUSTRIES (JP) 2019-02-06 EP disclosed
US-20180043678-A1 LITHOGRAPHIC PRINTING ORIGINAL PLATE, METHOD FOR PRODUCING LITHOGRAPHIC PRINTING PLATE USING SAME, AND METHOD FOR PRODUCING PRINTED MATTER TORAY INDUSTRIES, INC. (JP) 2018-02-15 US disclosed
EP-3267255-A1 LITHOGRAPHIC PRINTING ORIGINAL PLATE, METHOD FOR PRODUCING LITHOGRAPHIC PRINTING PLATE USING SAME, AND METHOD FOR PRODUCING PRINTED MATTER Toray Industries, Inc. (JP) 2018-01-10 EP disclosed
CN-107430342-A Original edition of lithographic printing plate, use the manufacture method of its lithographic plate and the manufacture method of printed article 东丽株式会社 2017-12-01 CN disclosed
US-20170320312-A1 METHOD FOR MANUFACTURING PRINTED MATTER TORAY INDUSTRIES, INC. (JP) 2017-11-09 US disclosed
US-6777156-B1 HIGH SENSITIVITY AND HIGH IMAGE REPRODUCIBILITY; EASILY MADE WITHOUT WATER TORAY INDUSTRIES, INC. (JP) 2004-08-17 US disclosed
US-20030228540-A1 Heat sensitive elements; organometallic compound TORAY INDUSTRIES, INC. (JP) 2003-12-11 US disclosed
US-6344306-B1 DECOMPOSITION PRODUCT PRODUCED AT AN INTERFACE BETWEEN THE INK ACCEPTING LAYER AND THE SILICONE RUBBER LAYER BY EXPOSURE OF THE PRINTING PLATE PRECURSOR TO A LASER BEAM TORAY INDUSTRIES, INC. (JP) 2002-02-05 US disclosed
US-6284433-B1 IMAGEWISELY IRRADIATING PRECURSOR OF PRINTING PLATE WITH LASER BEAM, PRE-TREATING PRECURSOR WITH GLYCOL COMPOUND AND/OR A GLYCOL ETHER COMPOUND; REMOVING INK REPELLENT LAYER WHEREIN HEAT SENSITIVE LAYER IS PARTIALLY LEFT ON PRINTING PLATE TORAY INDUSTRIES, INC. (JP) 2001-09-04 US disclosed
EP-1038669-A1 Method of producing directly imageable waterless planographic printing plate TORAY INDUSTRIES, INC. (JP) 2000-09-27 EP disclosed
EP-1036654-A1 Directly imageable waterless planographic printing plate precursor and plate TORAY INDUSTRIES, INC. (JP) 2000-09-20 EP disclosed
EP-0914942-A2 Directly imageable waterless planographic printing plate precursor and a method of producing planographic printing plates TORAY INDUSTRIES, INC. (JP) 1999-05-12 EP disclosed
EP-0267378-B1 TROPOLONE DERIVATIVES AS AN ANTI-MYCOPLASMA AGENT SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1992-11-04 EP disclosed
US-4950686-A Anti-mycoplasma agent SHIONOGI & CO., LTD. (JP) 1990-08-21 US disclosed
EP-0267378-A2 Tropolone derivatives as an anti-mycoplasma agent SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1988-05-18 EP disclosed