Troclosene

Troclosene

SCHEMBL531397

O=c1[nH]c(=O)n(Cl)c(=O)n1Cl.[NaH].[NaH]

nearest known ligand 0.30

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Troclosene SCHEMBL21812529 0.97
Troclosene SCHEMBL27499958 0.97
Troclosene SCHEMBL166386 0.97 APEX1 (0.31) APEX1
Symclosene SCHEMBL5923704 0.94 APEX1 (0.30) APEX1
Troclosene SCHEMBL6674436 0.94 APEX1 (0.30) APEX1
Troclosene SCHEMBL9083160 0.94 APEX1 (0.30) APEX1
Troclosene SCHEMBL9081895 0.94 APEX1 (0.30) APEX1
Troclosene SCHEMBL2832154 0.94 APEX1 (0.30) APEX1
Troclosene SCHEMBL31099328 0.91
Troclosene SCHEMBL11377335 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019002569-A1 METHOD FOR BREEDING HYBRID PLANTS UNIVERSITY OF LJUBLJANA (SI) 2019-01-03 WO disclosed
US-20190000024-A1 Method for Breeding Hybrid Plants UNIVERSITY OF LJUBLJANA (SI) 2019-01-03 US disclosed
US-8841283-B2 Methods for the preparation of drospirenone and intermediates thereof NEWCHEM S.P.A. (IT) 2014-09-23 US disclosed
EP-2601206-A1 METHODS FOR THE PREPARATION OF DROSPIRENONE AND INTERMEDIATES THEREOF Newchem S.p.A. (IT) 2013-06-12 EP disclosed
US-20130131335-A1 METHODS FOR THE PREPARATION OF DROSPIRENONE AND INTERMEDIATES THEREOF NEWCHEM S.P.A. (IT) 2013-05-23 US disclosed
EP-2415778-B1 Methods for the preparation of Drospirenone and intermediates thereof NEWCHEM S P A (IT) 2013-05-15 EP disclosed
WO-2012016860-A1 METHODS FOR THE PREPARATION OF DROSPIRENONE AND INTERMEDIATES THEREOF NEWCHEM S.P.A. (IT) 2012-02-09 WO disclosed
EP-2415778-A1 Methods for the preparation of Drospirenone and intermediates thereof Newchem S.p.A. (IT) 2012-02-08 EP disclosed
US-7977299-B2 Treated oxidizing agent, detergent composition containing a treated oxidizing agent, and methods for producing ECOLAB USA INC. (US) 2011-07-12 US disclosed
US-20090018046-A1 TREATED OXIDIZING AGENT, DETERGENT COMPOSITION CONTAINING A TREATING OXIDIZING AGENT, AND METHODS FOR PRODUCING ECOLAB INC. (US) 2009-01-15 US disclosed
US-20060040846-A1 Treated oxidizing agent, detergent composition containing a treated oxidizing agent, and methods for producing ECOLAB USA INC. 2006-02-23 US disclosed
WO-2005006862-A2 ODOR-MITIGATING COMPOSITIONS SL PARKHURST CORPORATION (US) 2005-01-27 WO disclosed
US-20050008608-A1 Odor-mitigating compositions SL PARKHURST CORPORATION 2005-01-13 US disclosed
EP-0315477-B1 METHOD FOR THE TREATMENT OF WOOL PRECISION PROCESSES TEXTILES (GB) 1993-08-18 EP disclosed
US-5087266-A Oxidative pretreatment; reacting with amino and silicone polymer PRECISION PROCESSES (TEXTILES) LIMITED (GB) 1992-02-11 US disclosed
EP-0315477-A2 Method for the treatment of wool PRECISION PROCESSES TEXTILES (GB) 1989-05-10 EP disclosed
US-4460490-A Lavatory cleansing blocks JEYES GROUP LIMITED (GB) 1984-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130131335-A1 METHODS FOR THE PREPARATION OF DROSPIRENONE AND INTERMEDIATES THEREOF CYP17A1, CYP21A2, CYP19A1 APEX1 1566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.