SCHEMBL5314047

SCHEMBL5314047

Cc1cccc(-n2nnc(C3CCCCN3C(=O)OC(C)(C)C)n2)c1

nearest known ligand 0.74

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CPT1A P50416 5/20 0.52
CPT2 P23786 3/20 0.51
MAPT P10636 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
GPR119 Q8TDV5 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5303450 0.90 CPT1A (0.52) CPT1ACPT2
SCHEMBL5303447 0.90 CPT1A (0.52) CPT1ACPT2
SCHEMBL4059432 0.89 CPT1A (0.52) CPT1ACPT2
SCHEMBL3963483 0.89 CPT1A (0.52) CPT1ACPT2
SCHEMBL2894183 0.87 POLB (0.49) CPT1ACPT2MAPTNPSR1
SCHEMBL2894182 0.87 POLB (0.49) CPT1ACPT2MAPTNPSR1
SCHEMBL3966278 0.87 CPT1A (0.52) CPT1ACPT2
SCHEMBL3962625 0.87 CPT1A (0.52) CPT1ACPT2
SCHEMBL8228619 0.86 CPT1A (0.48) CPT1ACPT2MAPTNPSR1
SCHEMBL2890738 0.86 CPT1A (0.48) CPT1ACPT2MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007039782-A1 TETRAZOLE DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS Richter Gedeon Vegyészeti Gyár Rt. (HU) 2007-04-12 WO disclosed