SCHEMBL5314075

SCHEMBL5314075

C[C@@H](C(=O)N(CCN)CC1CC1)N1CCC(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5225975 0.99 F10 (0.98) F10
SCHEMBL5225701 0.93 F10 (1.00) F10
SCHEMBL5222932 0.91 F10 (1.00) F10
SCHEMBL5261021 0.90 F10 (1.00) F10
SCHEMBL5226109 0.90 F10 (1.00) F10
SCHEMBL5224352 0.90 F10 (1.00) F10
SCHEMBL5257474 0.90 F10 (1.00) F10
SCHEMBL5228208 0.90 F10 (0.87) F10
SCHEMBL5264274 0.90 F10 (0.87) F10
SCHEMBL5222636 0.89 F10 (1.00) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1444201-B1 2-(3-SULFONYLAMINO-2-OXOPYRROLIDIN-1-YL)PROPANAMIDES AS FACTOR XA INHIBITORS GLAXO GROUP LTD (GB) 2007-09-12 EP claimed