Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.46 |
| ▸ | MET | P08581 | 7/20 | 0.41 |
| ▸ | IKBKB | O14920 | 3/20 | 0.41 |
| ▸ | CSF1R | P07333 | 2/20 | 0.41 |
| ▸ | CPB1 | P15086 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314156 | 1.00 | HRH3 (0.46) | HRH3METIKBKBCSF1RCPB1 | |
| SCHEMBL3204427 | 0.90 | HRH3 (0.54) | HRH3METIKBKBCSF1RATR | |
| SCHEMBL3200739 | 0.90 | HRH3 (0.54) | HRH3METIKBKBCSF1RATR | |
| SCHEMBL3198036 | 0.79 | HRH3 (0.56) | HRH3METIKBKBCSF1RATR | |
| SCHEMBL3196722 | 0.79 | HRH3 (0.54) | HRH3METIKBKBCSF1RATR | |
| SCHEMBL3196729 | 0.79 | HRH3 (0.54) | HRH3METIKBKBCSF1RATR | |
| SCHEMBL3198018 | 0.79 | HRH3 (0.56) | HRH3METIKBKBCSF1RATR | |
| SCHEMBL3196699 | 0.78 | HRH3 (0.57) | HRH3METIKBKBCSF1RATR | |
| SCHEMBL3196709 | 0.78 | HRH3 (0.57) | HRH3METIKBKBCSF1RATR | |
| SCHEMBL3194658 | 0.77 | HRH3 (0.53) | HRH3METIKBKBCSF1RATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784400-A1 | HISTAMINE H3 RECEPTOR AGENTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2007-05-16 | — | — | EP | claimed |
| WO-2006023462-A1 | HISTAMINE H3 RECEPTOR AGENTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2006-03-02 | — | — | WO | claimed |