Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.69 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | LDHB | P07195 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30295320 | 0.87 | ESR1 (0.45) | ESR1ESR2ALDH1A1L3MBTL1LMNA | |
| SCHEMBL19866165 | 0.85 | ESR1 (0.43) | ESR1ESR2ALDH1A1L3MBTL1LMNA | |
| SCHEMBL11154712 | 0.83 | ESR2 (1.00) | ESR1ESR2ALDH1A1L3MBTL1LMNA | |
| SCHEMBL269110 | 0.83 | ESR2 (1.00) | ESR1ESR2ALDH1A1L3MBTL1LMNA | |
| SCHEMBL2131572 | 0.83 | ESR2 (1.00) | ESR1ESR2ALDH1A1L3MBTL1LMNA | |
| SCHEMBL13379654 | 0.83 | ESR2 (1.00) | ESR1ESR2ALDH1A1L3MBTL1LMNA | |
| SCHEMBL2131554 | 0.83 | ESR2 (1.00) | ESR1ESR2ALDH1A1L3MBTL1LMNA | |
| SCHEMBL10777847 | 0.83 | ESR2 (1.00) | ESR1ESR2ALDH1A1L3MBTL1LMNA | |
| SCHEMBL13379655 | 0.83 | ESR2 (1.00) | ESR1ESR2ALDH1A1L3MBTL1LMNA | |
| SCHEMBL13379657 | 0.83 | ESR2 (1.00) | ESR1ESR2ALDH1A1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056500-A2 | COMPOUNDS WITH ACTIVITY AT ESTROGEN RECEPTORS | ACADIA PHARMACEUTICALS INC. (US) | 2007-05-18 | — | — | WO | disclosed |