Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 15/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 15/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 15/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 15/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 15/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 15/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 15/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 15/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 15/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 15/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 15/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5317149 | 0.89 | HDAC3 (0.70) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5316731 | 0.84 | HDAC3 (0.68) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5318016 | 0.80 | HDAC3 (0.76) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5315984 | 0.79 | HDAC3 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5315570 | 0.78 | HDAC3 (0.68) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4778838 | 0.78 | HDAC3 (0.77) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4795224 | 0.76 | HDAC3 (0.76) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5331144 | 0.76 | HDAC3 (0.78) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5185638 | 0.75 | MAPT (0.56) | ITGB3ITGA2B | |
| SCHEMBL5315375 | 0.74 | HDAC3 (0.79) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007067994-A1 | INHIBITORS OF HISTONE DEACETYLASE FOR THE TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2007-06-14 | — | — | WO | disclosed |