Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6912472 | 0.88 | PTGS1 (0.58) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL6912468 | 0.88 | PTGS1 (0.58) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL1049056 | 0.87 | PTGS1 (0.47) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL14020500 | 0.86 | PTGS1 (0.50) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL30358285 | 0.86 | PTGS1 (0.67) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL9561403 | 0.86 | PTGS1 (0.67) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL2353755 | 0.86 | PTGS1 (0.67) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL10547121 | 0.86 | PTGS1 (0.67) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL31435869 | 0.84 | PTGS1 (0.65) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL11833855 | 0.81 | PTGS1 (0.80) | PTGS1MEN1CYP2D6KMT2AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058504-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |