Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 9/20 | 0.40 |
| ▸ | RAB9A | P51151 | 9/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312761 | 0.89 | LCK (0.41) | LCKNPC1RAB9ABRAFKDR | |
| SCHEMBL5314220 | 0.89 | LCK (0.41) | LCKBRAFKDR | |
| SCHEMBL5313961 | 0.88 | LCK (0.45) | LCKBRAFKDR | |
| SCHEMBL5314588 | 0.83 | LCK (0.41) | LCKNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5316887 | 0.81 | LCK (0.38) | LCKMAPTKDM4EBRAFKDR | |
| SCHEMBL5315254 | 0.81 | MAPT (0.42) | LCKNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL5314806 | 0.81 | LCK (0.41) | LCKBRAFKDR | |
| SCHEMBL5314751 | 0.80 | LCK (0.50) | LCKBRAFKDR | |
| SCHEMBL5314682 | 0.80 | LCK (0.43) | LCKBRAFKDR | |
| SCHEMBL5312683 | 0.80 | LCK (0.39) | LCKALDH1A1BRAFKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |