⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8397867 | 1.00 | — | — | |
| SCHEMBL22907258 | 0.78 | ANPEP (0.32) | — | |
| SCHEMBL16581521 | 0.70 | — | — | |
| SCHEMBL918423 | 0.70 | — | — | |
| SCHEMBL1986587 | 0.70 | — | — | |
| SCHEMBL12693922 | 0.70 | — | — | |
| SCHEMBL918669 | 0.70 | — | — | |
| SCHEMBL20885382 | 0.70 | — | — | |
| SCHEMBL822825 | 0.70 | — | — | |
| SCHEMBL919096 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210198218-A1 | COMPOUNDS FOR THERAPEUTIC USE | DART NEUROSCIENCE LLC (US) | 2021-07-01 | — | — | US | disclosed |
| EP-3507277-B1 | HYDROXYNORKETAMINE DERIVATIVES FOR THE TREATMENT OF DISORDERS | DART NEUROSCIENCE LLC (US) | 2020-11-18 | — | — | EP | disclosed |
| US-10738018-B2 | Compounds for therapeutic use | DART NEUROSCIENCE, LLC (US) | 2020-08-11 | — | — | US | disclosed |
| EP-3507277-A1 | HYDROXYNORKETAMINE DERIVATIVES FOR THE TREATMENT OF CNS DISORDERS | Dart NeuroScience LLC (US) | 2019-07-10 | — | — | EP | disclosed |
| US-20180251435-A1 | COMPOUNDS FOR THERAPEUTIC USE | DART NEUROSCIENCE LLC (US) | 2018-09-06 | — | — | US | disclosed |
| US-9963435-B2 | Compounds for therapeutic use | DART NEUROSCIENCE, LLC (US) | 2018-05-08 | — | — | US | disclosed |
| WO-2018044896-A1 | HYDROXYNORKETAMINE DERIVATIVES FOR THE TREATMENT OF CNS DISORDERS | DART NEUROSCIENCE, LLC (US) | 2018-03-08 | — | — | WO | disclosed |
| US-20180057470-A1 | COMPOUNDS FOR THERAPEUTIC USE | DART NEUROSCIENCE, LLC | 2018-03-01 | — | — | US | disclosed |
| US-20070112015-A1 | Substituted dihydropyridines and methods of use | CHEMOCENTRYX, INC. (US) | 2007-05-17 | — | — | US | disclosed |
| WO-2007051062-A2 | SUBSTITUTED DIHYDROPYRIDINES AND METHODS OF USE | CHEMOCENTRYX, INC. (US) | 2007-05-03 | — | — | WO | disclosed |
| EP-1701695-A1 | MEROCYANINE DERIVATIVES FOR COSMETIC USE | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2006-09-20 | — | — | EP | disclosed |
| WO-2005058269-A1 | MEROCYANINE DERIVATIVES FOR COSMETIC USE | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-06-30 | — | — | WO | disclosed |
| US-3948993-A | FROM A CYANOALKYLATED KETONE, WATER, MINERAL ACID | DEUTSCHE TEXACO AKTIENGESELLSCHAFT (DT) | 1976-04-06 | — | — | US | disclosed |