Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.77 |
| ▸ | PKM | P14618 | 1/20 | 0.77 |
| ▸ | MAPT | P10636 | 9/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.76 |
| ▸ | TP53 | P04637 | 2/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.74 |
| ▸ | THRB | P10828 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11242122 | 0.87 | MAPT (0.75) | KMT2AMEN1PKMMAPTSMN1; SMN2 | |
| SCHEMBL5501450 | 0.85 | KMT2A (0.76) | KMT2AMEN1PKMMAPTSMN1; SMN2 | |
| SCHEMBL2045638 | 0.85 | KMT2A (0.79) | KMT2AMEN1PKMMAPTSMN1; SMN2 | |
| SCHEMBL5505918 | 0.84 | KMT2A (0.77) | KMT2AMEN1PKMMAPTSMN1; SMN2 | |
| SCHEMBL5673839 | 0.84 | MAPT (0.71) | KMT2AMEN1PKMMAPTSMN1; SMN2 | |
| SCHEMBL5506586 | 0.83 | KMT2A (0.76) | KMT2AMEN1PKMMAPTSMN1; SMN2 | |
| SCHEMBL5505490 | 0.83 | KMT2A (0.65) | KMT2AMEN1PKMMAPTSMN1; SMN2 | |
| SCHEMBL9175601 | 0.82 | MEN1 (0.74) | KMT2AMEN1PKMMAPTSMN1; SMN2 | |
| SCHEMBL530155 | 0.82 | KMT2A (0.78) | KMT2AMEN1PKMMAPTSMN1; SMN2 | |
| SCHEMBL5501524 | 0.82 | KMT2A (0.74) | KMT2AMEN1PKMMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | claimed |
| WO-2007047579-A2 | A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-04-26 | — | — | WO | claimed |