Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.51 |
| ▸ | PADI1 | Q9ULC6 | 3/20 | 0.51 |
| ▸ | PADI4 | Q9UM07 | 3/20 | 0.51 |
| ▸ | PADI2 | Q9Y2J8 | 3/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.50 |
| ▸ | ALB | P02768 | 3/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | C3AR1 | Q16581 | 2/20 | 0.46 |
| ▸ | PADI6 | Q6TGC4 | 1/20 | 0.45 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13969386 | 0.91 | ALB (0.53) | PDE4APADI1PADI4PADI2PDE4B | |
| SCHEMBL1981102 | 0.90 | PADI4 (0.65) | PDE4APADI1PADI4PADI2PDE4B | |
| SCHEMBL10801725 | 0.87 | FOLH1 (0.59) | FOLH1 | |
| SCHEMBL8975695 | 0.87 | FOLH1 (0.59) | FOLH1 | |
| SCHEMBL15231556 | 0.83 | C3AR1 (0.60) | PDE4APADI1PADI4PADI2PDE4B | |
| SCHEMBL11544593 | 0.83 | FOLH1 (0.60) | FOLH1 | |
| SCHEMBL10801036 | 0.83 | FOLH1 (0.60) | FOLH1 | |
| SCHEMBL11576579 | 0.82 | FOLH1 (0.60) | FOLH1 | |
| SCHEMBL1983969 | 0.81 | FOLH1 (0.47) | PDE4APADI1PADI4PADI2PDE4B | |
| SCHEMBL188590 | 0.81 | C3AR1 (0.52) | PDE4APADI1PADI4PADI2PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056389-A2 | SYNTHESIS AND USE OF NOVEL INHIBITORS AND INACTIVATORS OF PROTEIN ARGININE DEIMINASES | UNIVERSITY OF SOUTH CAROLINA (US) | 2007-05-18 | — | — | WO | disclosed |