Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.40 |
| ▸ | PPARA | Q07869 | 7/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5309702 | 0.91 | PDE10A (0.43) | PPARGPPARAPTPN1PDE10ASMN1; SMN2 | |
| SCHEMBL5309698 | 0.91 | PDE10A (0.43) | PPARGPPARAPTPN1PDE10ASMN1; SMN2 | |
| SCHEMBL14530972 | 0.87 | PDE10A (0.43) | PPARGPPARAPTPN1PDE10ASMN1; SMN2 | |
| SCHEMBL5310846 | 0.87 | PDE10A (0.43) | PPARGPPARAPTPN1PDE10ASMN1; SMN2 | |
| SCHEMBL5316013 | 0.86 | PTPN11 (0.42) | PPARGPPARAPTPN1PDE10AHAVCR2 | |
| SCHEMBL5316012 | 0.86 | PTPN11 (0.42) | PPARGPPARAPTPN1PDE10AHAVCR2 | |
| SCHEMBL5312944 | 0.86 | PTPN1 (0.40) | PPARGPPARAPTPN1PDE10AHAVCR2 | |
| SCHEMBL5312940 | 0.86 | PTPN1 (0.40) | PPARGPPARAPTPN1PDE10AHAVCR2 | |
| SCHEMBL5311834 | 0.85 | MAPT (0.47) | PPARGPPARAPTPN1HAVCR2CYP1A2 | |
| SCHEMBL5311831 | 0.85 | MAPT (0.47) | PPARGPPARAPTPN1HAVCR2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058504-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |