Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12920665 | 0.75 | SRC (0.41) | SRCIDO1MAPT | |
| SCHEMBL5493982 | 0.75 | MAPT (0.36) | SRCIDO1MAPT | |
| SCHEMBL26121351 | 0.75 | SRC (0.34) | SRCIDO1MAPT | |
| SCHEMBL13377381 | 0.73 | SRC (0.37) | SRCMAPT | |
| SCHEMBL439909 | 0.71 | SRC (0.32) | SRCMAPT | |
| SCHEMBL26119056 | 0.71 | SRC (0.32) | SRC | |
| SCHEMBL31055794 | 0.71 | MAPT (0.38) | SRCMAPT | |
| SCHEMBL21672753 | 0.71 | SRC (0.35) | SRC | |
| SCHEMBL26122962 | 0.71 | SRC (0.32) | SRC | |
| SCHEMBL18185941 | 0.69 | LCK (0.36) | SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740591-A1 | 6,6-BICYCLIC RING SUBSTITUTED HETEROBICYCLIC PROTEIN KINASE INHIBITORS | OSI Pharmaceuticals, Inc. (US) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005097800-A1 | 6,6-BICYCLIC RING SUBSTITUTED HETEROBICYCLIC PROTEIN KINASE INHIBITORS | OSI PHARMACEUTICALS, INC. (US) | 2005-10-20 | — | — | WO | disclosed |