Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3047422 | 0.78 | TSHR (0.36) | TSHRDPP4 | |
| SCHEMBL18625549 | 0.76 | TSHR (0.37) | TSHR | |
| SCHEMBL1444834 | 0.76 | DPP4 (0.39) | DPP4HPGDRIPK1 | |
| SCHEMBL20501570 | 0.74 | HPGD (0.35) | DPP4HPGD | |
| SCHEMBL20501432 | 0.73 | — | — | |
| SCHEMBL12891039 | 0.72 | TSHR (0.48) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12712358 | 0.72 | TSHR (0.48) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12712359 | 0.72 | TSHR (0.48) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27836229 | 0.71 | — | — | |
| SCHEMBL16353786 | 0.71 | TSHR (0.33) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007081091-A1 | RHODANDSE DERIVARIVES, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2007-07-19 | — | — | WO | disclosed |