Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.85 |
| ▸ | PPARA | Q07869 | 19/20 | 0.85 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5317177 | 1.00 | PPARG (0.85) | PPARGPPARARXRARXRBRXRG | |
| SCHEMBL4152263 | 0.93 | PPARG (0.82) | PPARGPPARARXRARXRBRXRG | |
| SCHEMBL4152264 | 0.93 | PPARG (0.82) | PPARGPPARARXRARXRBRXRG | |
| SCHEMBL4151502 | 0.92 | PPARG (1.00) | PPARGPPARARXRARXRBRXRG | |
| SCHEMBL4151504 | 0.92 | PPARG (1.00) | PPARGPPARARXRARXRBRXRG | |
| SCHEMBL4144244 | 0.89 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL4147625 | 0.89 | PPARG (0.84) | PPARGPPARARXRARXRBRXRG | |
| SCHEMBL4146970 | 0.89 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL4146973 | 0.89 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL4147624 | 0.89 | PPARG (0.84) | PPARGPPARARXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844015-A2 | NOVEL HETEROCYCLIC OXIME DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier (FR) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006079719-A2 | NOVEL HETEROCYCLIC OXIME DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2006-08-03 | — | — | WO | disclosed |