Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16047347 | 0.77 | MAPT (0.34) | MAPTKDM4EALDH1A1HTTGAA | |
| SCHEMBL31057213 | 0.77 | MAPT (0.34) | MAPTKDM4EALDH1A1HTTGAA | |
| SCHEMBL30714365 | 0.77 | MAPT (0.34) | MAPTKDM4EALDH1A1HTTGAA | |
| SCHEMBL10857949 | 0.77 | MAPT (0.34) | MAPTKDM4EALDH1A1HTTGAA | |
| SCHEMBL30937768 | 0.77 | MAPT (0.34) | MAPTKDM4EALDH1A1HTTGAA | |
| SCHEMBL30640462 | 0.77 | MAPT (0.42) | MAPTKDM4EALDH1A1HTTGAA | |
| SCHEMBL21505452 | 0.77 | MAPT (0.42) | MAPTKDM4EALDH1A1HTTGAA | |
| SCHEMBL20562476 | 0.77 | POLB (0.42) | MAPTKDM4EALDH1A1HTTGAA | |
| SCHEMBL16048277 | 0.77 | MAPT (0.34) | MAPTKDM4EALDH1A1HTTGAA | |
| SCHEMBL29352476 | 0.76 | KDM4E (0.45) | MAPTKDM4EALDH1A1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362854-B1 | Benzo[b[thiophene derivatives and process for producing the same | TEIJIN PHARMA LTD (JP) | 2007-10-31 | — | — | EP | disclosed |