Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 20/20 | 0.67 |
| ▸ | CNR2 | P34972 | 1/20 | 0.66 |
| ▸ | TACR2 | P21452 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2487148 | 0.84 | CNR1 (0.74) | CNR1CNR2TACR2 | |
| SCHEMBL3855806 | 0.84 | CNR1 (0.50) | CNR1CNR2TACR2 | |
| SCHEMBL2704767 | 0.80 | CNR1 (1.00) | CNR1CNR2TACR2 | |
| SCHEMBL2704666 | 0.80 | CNR1 (1.00) | CNR1CNR2TACR2 | |
| SCHEMBL2702760 | 0.80 | CNR1 (1.00) | CNR1CNR2TACR2 | |
| SCHEMBL5271437 | 0.80 | CNR1 (0.96) | CNR1CNR2TACR2 | |
| SCHEMBL9931290 | 0.80 | CNR1 (1.00) | CNR1CNR2TACR2 | |
| SCHEMBL3848696 | 0.80 | CNR1 (0.96) | CNR1CNR2TACR2 | |
| SCHEMBL2702016 | 0.79 | CNR1 (1.00) | CNR1CNR2TACR2 | |
| SCHEMBL2702019 | 0.79 | CNR1 (1.00) | CNR1CNR2TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1868999-A1 | PYRIDINE-3-CARBOXAMIDE DERIVATIVES AS CB1 INVERSE AGONISTS | F. Hoffmann-Roche AG (CH) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006106054-A1 | PYRIDINE-3-CARBOXAMIDE DERIVATIVES AS CB1 INVERSE AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-10-12 | — | — | WO | disclosed |