Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5319146 | 0.88 | GRM2 (0.64) | GRM2 | |
| SCHEMBL5319819 | 0.86 | GRM2 (0.64) | GRM2 | |
| SCHEMBL5320205 | 0.85 | GRM2 (0.63) | GRM2 | |
| SCHEMBL5320067 | 0.84 | GRM2 (0.61) | GRM2 | |
| SCHEMBL5317630 | 0.83 | GRM2 (0.66) | GRM2 | |
| SCHEMBL5320047 | 0.83 | GRM2 (0.46) | GRM2 | |
| SCHEMBL5322180 | 0.80 | GRM2 (0.42) | GRM2 | |
| SCHEMBL4944338 | 0.80 | GRM2 (1.00) | GRM2 | |
| SCHEMBL5321096 | 0.79 | GRM2 (0.61) | GRM2 | |
| SCHEMBL5318946 | 0.79 | GRM2 (0.44) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773774-A2 | HETEROCYCLIC ACETOPHENONE POTENTIATORS OF METABOTROPIC GLUTAMATE RECEPTORS | Merck & Co., Inc. (US) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006014918-A2 | HETEROCYCLIC ACETOPHENONE POTENTIATORS OF METABOTROPIC GLUTAMATE RECEPTORS | MERCK & CO., INC. (US) | 2006-02-09 | — | — | WO | disclosed |