Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15690447 | 1.00 | CHRM2 (0.42) | CHRM2CHRM1CHRM3HSD17B10HPGD | |
| SCHEMBL26893965 | 0.90 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HSD17B10HPGD | |
| SCHEMBL20729579 | 0.90 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HSD17B10HPGD | |
| SCHEMBL27043970 | 0.90 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HSD17B10HPGD | |
| SCHEMBL72827 | 0.90 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HSD17B10HPGD | |
| SCHEMBL91558 | 0.90 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HSD17B10HPGD | |
| SCHEMBL692637 | 0.90 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HSD17B10HPGD | |
| SCHEMBL8304417 | 0.90 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HSD17B10HPGD | |
| SCHEMBL200978 | 0.90 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HSD17B10HPGD | |
| SCHEMBL200722 | 0.90 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844062-A2 | INHIBITORS OF DNA METHYLTRANSFERASE | Methylgene, Inc. (CA) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006078752-A2 | INHIBITORS OF DNA METHYLTRANSFERASE | METHYLGENE, INC. (CA) | 2006-07-27 | — | — | WO | disclosed |