Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2197414 | 0.92 | KCNH2 (0.42) | MEN1KMT2AADRB2ADRB1ADRB3 | |
| SCHEMBL2194726 | 0.91 | KCNA5 (0.46) | S1PR1FFAR1ADRB2ADRB1ADRB3 | |
| SCHEMBL2196293 | 0.90 | BRD4 (0.38) | KMT2AADRB2ADRB1ADRB3CYP3A4 | |
| SCHEMBL2198676 | 0.89 | KMT2A (0.52) | MEN1KMT2AS1PR1FFAR1NPY5R | |
| SCHEMBL2468729 | 0.88 | KCNA5 (0.44) | FFAR1ADRB2ADRB1ADRB3CYP3A4 | |
| SCHEMBL3115056 | 0.87 | CYP3A4 (0.43) | MEN1KMT2AS1PR1CYP3A4CYP3A5 | |
| SCHEMBL2198960 | 0.86 | CYP11B1 (0.39) | S1PR1ADRB2ADRB1ADRB3CYP3A4 | |
| SCHEMBL2198157 | 0.85 | KCNA5 (0.43) | ADRB2ADRB1ADRB3CYP3A4NPY5R | |
| SCHEMBL12211493 | 0.82 | KCNA5 (0.45) | MEN1KMT2AS1PR1FFAR1CYP3A4 | |
| SCHEMBL2196056 | 0.80 | ATM (0.49) | KMT2AADRB2ADRB1ADRB3CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1794167-A1 | SUBSTITUTED ISOXAZOLES AS FUNGICIDES | Syngenta Limited (GB) | 2007-06-13 | — | — | EP | disclosed |
| WO-2006031631-A1 | SUBSTITUTED ISOXAZOLES AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2006-03-23 | — | — | WO | disclosed |