SCHEMBL532019

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL531822	0.92	HPGD (0.56)	POLBKDRPDE3BPDE3AERN1
	SCHEMBL532007	0.83	KDR (0.53)	POLBKDRPDE3BPDE3ABRD4
	SCHEMBL532744	0.82	KDR (0.52)	KDRPDE3BPDE3AERN1ABL1
	SCHEMBL532605	0.82	POLB (0.53)	POLBPDE3BPDE3AABL1HPGD
	SCHEMBL531713	0.80	KDR (0.58)	KDRPDE3BPDE3ABRD4SMYD3
	SCHEMBL532077	0.77	KDR (0.55)	KDRPDE3BPDE3ASMYD3PARP1
	SCHEMBL7001705	0.76	PARP1 (0.64)	KDRPDE3BPDE3AMEN1KMT2A
	SCHEMBL25602693	0.74	POLB (0.53)	POLBERN1BRD4HPGDMEN1
	SCHEMBL531913	0.74	PARP1 (0.59)	POLBKDRERN1HPGDRAB9A
	SCHEMBL531866	0.73	KDR (0.48)	KDRPDE3BPDE3ABRD4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.