Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30015741 | 0.83 | ATM (0.70) | ATML3MBTL1KAT6AKMT2AMEN1 | |
| SCHEMBL6758999 | 0.83 | ATM (0.66) | ATML3MBTL1KAT6AKMT2AMEN1 | |
| SCHEMBL3386980 | 0.83 | ATM (0.66) | ATML3MBTL1KAT6AKMT2AALDH1A1 | |
| SCHEMBL1348672 | 0.83 | ATM (0.70) | ATML3MBTL1KAT6AKMT2AMEN1 | |
| SCHEMBL1348562 | 0.81 | ATM (0.62) | ATML3MBTL1KAT6AKMT2AALDH1A1 | |
| SCHEMBL2377180 | 0.81 | ATM (0.67) | ATML3MBTL1KAT6AKMT2AALDH1A1 | |
| SCHEMBL1348621 | 0.80 | ATM (0.61) | ATML3MBTL1KAT6AKMT2AMEN1 | |
| SCHEMBL29334656 | 0.80 | ATM (0.61) | ATML3MBTL1KAT6AKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7966569 | 0.80 | ATM (0.61) | ATML3MBTL1KAT6AKMT2AALDH1A1 | |
| SCHEMBL12570968 | 0.80 | ATM (0.65) | ATML3MBTL1KAT6AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007108743-A2 | NOVEL QUINAZOLINES AS 5-HT6 MODULATORS II | ASTRAZENECA AB (SE) | 2007-09-27 | — | — | WO | disclosed |