SCHEMBL532066

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL532557	0.83	PARP1 (0.53)	PARP1ALDH1A1KDM4EDRD3DRD2
	SCHEMBL532590	0.83	PARP1 (0.53)	PARP1KDM4EDRD3DRD2DRD4
	SCHEMBL531594	0.82	PARP1 (0.72)	PARP1DRD3DRD2DRD4
	SCHEMBL10261018	0.79	PARP1 (0.53)	PARP1ALDH1A1KDM4EDRD3DRD2
	SCHEMBL532542	0.79	PARP1 (0.60)	PARP1
	SCHEMBL532018	0.77	PARP1 (0.51)	PARP1KDM4EDRD3DRD2DRD4
	SCHEMBL531881	0.74	PARP1 (0.75)	PARP1
	SCHEMBL532155	0.73	PARP1 (0.56)	PARP1MAPT
	SCHEMBL532641	0.73	PARP1 (0.75)	PARP1
	SCHEMBL532976	0.73	PARP1 (0.62)	PARP1DRD3DRD2DRD4SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.