Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.64 |
| ▸ | PPARG | P37231 | 16/20 | 0.64 |
| ▸ | PPARD | Q03181 | 16/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5275218 | 1.00 | PPARA (0.64) | PPARAPPARGPPARDTP53TSHR | |
| SCHEMBL5272851 | 1.00 | PPARA (0.64) | PPARAPPARGPPARDTP53TSHR | |
| SCHEMBL5273059 | 0.98 | PPARA (0.66) | PPARAPPARGPPARDTP53TSHR | |
| SCHEMBL5279460 | 0.98 | PPARA (0.66) | PPARAPPARGPPARDTP53TSHR | |
| SCHEMBL5274500 | 0.98 | PPARA (0.66) | PPARAPPARGPPARDTP53TSHR | |
| SCHEMBL5270860 | 0.96 | PPARA (0.58) | PPARAPPARGPPARD | |
| SCHEMBL5277810 | 0.95 | PPARA (0.61) | PPARAPPARGPPARD | |
| SCHEMBL5272898 | 0.94 | PPARA (0.58) | PPARAPPARGPPARD | |
| SCHEMBL5278459 | 0.93 | PPARA (0.59) | PPARAPPARGPPARD | |
| SCHEMBL14366189 | 0.92 | PPARA (0.61) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7301033-B2 | PPAR-activating compound | KOWA CO., LTD. (JP) | 2007-11-27 | — | — | US | disclosed |
| US-7301033-B2 | PPAR-activating compound | KOWA CO., LTD. (JP) | 2007-11-27 | — | — | US | disclosed |
| US-7301033-B2 | PPAR-activating compound | KOWA CO., LTD. (JP) | 2007-11-27 | — | — | US | disclosed |
| EP-1857447-A1 | PPAR-ACTIVATING COMPOUND | Kowa Company, Ltd. (JP) | 2007-11-21 | — | — | EP | disclosed |
| US-20060167058-A1 | PPAR-activating compound | KOWA CO., LTD. (JP) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167058-A1 | PPAR-activating compound | PPARA, PPARG, PPARD | PPARA 1/4885PPARG 2/4885PPARD 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.