Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CD69 | Q07108 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320718 | 1.00 | MAPK8 (0.40) | MAPK8MAPK9MAPK10ALOX15LMNA | |
| SCHEMBL5317820 | 0.86 | NPC1 (0.37) | ALDH1A1MEN1KMT2A | |
| SCHEMBL5317825 | 0.86 | NPC1 (0.37) | ALDH1A1MEN1KMT2A | |
| SCHEMBL4863074 | 0.86 | MAPK1 (0.39) | MAPK8MAPK9MAPK10LMNAHPGD | |
| SCHEMBL14196714 | 0.86 | MAPK1 (0.39) | MAPK8MAPK9MAPK10LMNAHPGD | |
| SCHEMBL5321196 | 0.84 | CYP3A4 (0.35) | ALDH1A1MEN1KMT2A | |
| SCHEMBL5321199 | 0.84 | CYP3A4 (0.35) | ALDH1A1MEN1KMT2A | |
| SCHEMBL5320440 | 0.83 | NPSR1 (0.40) | MAPK8MAPK9MAPK10MAPTALDH1A1 | |
| SCHEMBL14425277 | 0.73 | MAPK1 (0.40) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL4856100 | 0.73 | MAPK1 (0.38) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537117-B1 | BENZOTRIAZABICYCLIC DERIVATIVES AND USE THEREOF AS BETA-LACTAMASE INHIBITORS AND ANTI-BACTERIAL AGENTS | AVENTIS PHARMA SA (FR) | 2007-01-17 | — | — | EP | disclosed |