Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 16/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5269388 | 1.00 | PTGDR2 (0.58) | PTGDR2MEN1KMT2A | |
| SCHEMBL5269392 | 1.00 | PTGDR2 (0.58) | PTGDR2MEN1KMT2A | |
| SCHEMBL5269390 | 1.00 | PTGDR2 (0.58) | PTGDR2MEN1KMT2A | |
| SCHEMBL6070504 | 0.86 | PTGDR2 (0.56) | PTGDR2MEN1KMT2A | |
| SCHEMBL6070506 | 0.86 | PTGDR2 (0.56) | PTGDR2MEN1KMT2A | |
| SCHEMBL5372886 | 0.86 | PTGDR2 (0.56) | PTGDR2MEN1KMT2A | |
| SCHEMBL5318422 | 0.86 | PTGDR2 (0.56) | PTGDR2MEN1KMT2A | |
| SCHEMBL6071132 | 0.85 | MEN1 (0.56) | PTGDR2MEN1KMT2A | |
| SCHEMBL4123897 | 0.85 | PTGDR2 (0.58) | PTGDR2MEN1KMT2A | |
| SCHEMBL5376563 | 0.85 | MEN1 (0.56) | PTGDR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861372-A1 | PGD2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006091674-A1 | PGD2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2006-08-31 | — | — | WO | disclosed |