Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.38 |
| ▸ | MEN1 | O00255 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.38 |
| ▸ | RELA | Q04206 | 3/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4915044 | 0.83 | SMN1; SMN2 (0.55) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL4908655 | 0.80 | GAA (0.50) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL4913799 | 0.78 | NPC1 (0.44) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL4913185 | 0.77 | NPC1 (0.53) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL4915377 | 0.76 | MAPT (0.59) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL4916241 | 0.76 | DYRK1A (0.56) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL4427895 | 0.75 | EPHX2 (0.53) | MAPTMEN1KMT2AGAANPSR1 | |
| SCHEMBL4908696 | 0.75 | NPC1 (0.52) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL4913866 | 0.74 | TP53 (0.45) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL4922825 | 0.73 | NPC1 (0.58) | MEN1KMT2ASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007121154-A2 | SUBSTITUTED BENZOTHIAZOLE KINASE INHIBITORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-10-25 | — | — | WO | claimed |