Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 13/20 | 0.47 |
| ▸ | RET | P07949 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4882060 | 1.00 | PARP1 (0.50) | PARP1ARRETHDAC1HSD11B1 | |
| SCHEMBL30607714 | 0.87 | PARP1 (0.48) | PARP1ARRETHDAC1HSD11B1 | |
| SCHEMBL29384830 | 0.86 | PARP1 (0.50) | PARP1ARRETHDAC1HSD11B1 | |
| SCHEMBL5319559 | 0.85 | AR (0.49) | AR | |
| SCHEMBL4879996 | 0.85 | AR (0.49) | AR | |
| SCHEMBL4871818 | 0.82 | AR (0.49) | AR | |
| SCHEMBL1930266 | 0.77 | PARP1 (0.51) | PARP1RETHDAC1HSD11B1 | |
| SCHEMBL6703193 | 0.77 | PARP1 (0.51) | PARP1RETHDAC1HSD11B1 | |
| SCHEMBL30818801 | 0.76 | PARP1 (0.54) | PARP1ARHDAC1HSD11B1 | |
| Hydrochloric Acid SCHEMBL4880707 | 0.76 | AR (0.53) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007092391-A1 | ANDROGEN RECEPTOR MODULATORS AND METHODS OF TREATING DISEASE USING THE SAME | ACADIA PHARMACEUTICALS INC. (US) | 2007-08-16 | — | — | WO | disclosed |