Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 11/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CCKBR | P32239 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5323064 | 0.91 | PTH1R (0.75) | PTH1RCCKBR | |
| SCHEMBL5459291 | 0.88 | PTH1R (0.70) | PTH1RCCKBR | |
| SCHEMBL5320304 | 0.86 | PTH1R (0.81) | PTH1RCCKBR | |
| SCHEMBL5322976 | 0.86 | PTH1R (0.80) | PTH1RALDH1A1LMNAGAACCKBR | |
| SCHEMBL5329770 | 0.85 | PTH1R (0.85) | PTH1RCCKBR | |
| SCHEMBL14566539 | 0.85 | PTH1R (1.00) | PTH1RCCKBR | |
| SCHEMBL5327296 | 0.85 | PTH1R (0.84) | PTH1RCCKBR | |
| SCHEMBL5326270 | 0.84 | PTH1R (0.75) | PTH1RCCKBR | |
| SCHEMBL5327984 | 0.83 | PTH1R (0.80) | PTH1RCCKBR | |
| SCHEMBL14566326 | 0.83 | PTH1R (0.72) | PTH1RCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006129120-A9 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-03-22 | — | — | WO | disclosed |
| WO-2006129120-A2 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2006-12-07 | — | — | WO | disclosed |