Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 4/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5322682 | 0.91 | GRM2 (0.56) | GRM2DRD2DRD3DRD4 | |
| SCHEMBL5328515 | 0.89 | GRM2 (0.59) | GRM2DRD2DRD3DRD4 | |
| SCHEMBL4139191 | 0.83 | GRM2 (0.55) | GRM2DRD2DRD3DRD4 | |
| SCHEMBL4152281 | 0.81 | CYP2D6 (0.53) | GRM2DRD2DRD3DRD4 | |
| SCHEMBL5324285 | 0.79 | GRM2 (0.55) | GRM2DRD2DRD3DRD4 | |
| SCHEMBL5325773 | 0.79 | GRM2 (0.55) | GRM2DRD2DRD3DRD4 | |
| SCHEMBL5328000 | 0.79 | GRM2 (0.55) | GRM2DRD2DRD3DRD4 | |
| SCHEMBL5321874 | 0.79 | GRM2 (0.55) | GRM2DRD2DRD3DRD4 | |
| SCHEMBL5327996 | 0.79 | GRM2 (0.55) | GRM2DRD2DRD3DRD4 | |
| SCHEMBL4152111 | 0.79 | GRM2 (0.58) | GRM2DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135527-A2 | BENZIMIDAZOLYL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | disclosed |