Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 12/20 | 0.83 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.62 |
| ▸ | PYGL | P06737 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2713362 | 1.00 | GBA1 (0.83) | GBA1FUCA1PYGLCYP2D6 | |
| SCHEMBL2713369 | 1.00 | GBA1 (0.83) | GBA1FUCA1PYGLCYP2D6 | |
| SCHEMBL5327603 | 0.91 | GBA1 (1.00) | GBA1FUCA1PYGL | |
| SCHEMBL8186647 | 0.91 | GBA1 (1.00) | GBA1FUCA1PYGL | |
| SCHEMBL2713933 | 0.91 | GBA1 (1.00) | GBA1FUCA1PYGL | |
| SCHEMBL24008565 | 0.88 | FUCA1 (0.74) | GBA1FUCA1CYP2D6 | |
| SCHEMBL2268869 | 0.88 | FUCA1 (0.80) | GBA1FUCA1CYP2D6 | |
| SCHEMBL30287840 | 0.88 | FUCA1 (0.74) | GBA1FUCA1CYP2D6 | |
| SCHEMBL1857553 | 0.88 | FUCA1 (0.80) | GBA1FUCA1CYP2D6 | |
| SCHEMBL8187999 | 0.85 | GBA1 (0.77) | GBA1FUCA1PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007150064-A2 | METHOD FOR THE TREATMENT OF NEUROLOGICAL DISORDERS BY ENHANCING THE ACTIVITY OF β-GLUCOCEREBROSIDASE | AMICUS THERAPEUTICS, INC. (US) | 2007-12-27 | — | — | WO | disclosed |