⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11924600 | 0.72 | — | — | |
| SCHEMBL3681554 | 0.68 | — | — | |
| SCHEMBL4642951 | 0.68 | — | — | |
| Bromide SCHEMBL8931675 | 0.67 | — | — | |
| SCHEMBL7260527 | 0.60 | — | — | |
| SCHEMBL11924601 | 0.60 | — | — | |
| Imidazolinone SCHEMBL9200599 | 0.59 | — | — | |
| Imidazolinone SCHEMBL14994238 | 0.59 | — | — | |
| Imidazolinone SCHEMBL9391330 | 0.59 | — | — | |
| Imidazolinone SCHEMBL17493427 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111499644-B | Imidazo [1,5-a ] quinazoline-5 (4H) -ketone derivative and preparation method and application thereof | 苏州大学 | 2021-07-20 | — | — | CN | claimed |
| EP-0076199-B1 | TRIAZOLOQUINAZOLONES AND THEIR SALTS, PROCESS AND INTERMEDIATES FOR PREPARING THEM, THEIR USE AS MEDICINES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1986-12-30 | — | — | EP | claimed |
| CN-115362003-B | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-03-22 | — | — | CN | disclosed |
| CN-117736207-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-03-22 | — | — | CN | disclosed |
| CN-117396478-A | Diacylglycerol kinase modulating compounds | 吉利德科学公司 | 2024-01-12 | — | — | CN | disclosed |
| WO-2023205680-A1 | PI3Kα INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | WO | disclosed |
| CN-116332944-A | Tri-ring ubiquitin-specific protease 1 inhibitors and uses thereof | 轩竹生物科技股份有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-115362003-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2022-11-18 | — | — | CN | disclosed |
| WO-2007144669-A1 | PYRAZOLO[1,5-A]QUINAZOLIN-5(4H)-ONES AS INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2007-12-21 | — | — | WO | disclosed |
| EP-0076199-B1 | TRIAZOLOQUINAZOLONES AND THEIR SALTS, PROCESS AND INTERMEDIATES FOR PREPARING THEM, THEIR USE AS MEDICINES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1986-12-30 | — | — | EP | disclosed |
| EP-0076199-A2 | Triazoloquinazolones and their salts, process and intermediates for preparing them, their use as medicines and compositions containing them | ROUSSEL-UCLAF (FR) | 1983-04-06 | — | — | EP | disclosed |