Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 19/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | CTSA | P10619 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL531294 | 0.91 | CETP (0.51) | CETPNR1I2CTSA | |
| SCHEMBL531710 | 0.81 | CETP (0.50) | CETPNR1I2 | |
| SCHEMBL3305177 | 0.81 | CETP (0.68) | CETPNR1I2 | |
| SCHEMBL4183431 | 0.81 | CETP (0.67) | CETP | |
| SCHEMBL3554515 | 0.78 | CETP (0.59) | CETPNR1I2 | |
| SCHEMBL531635 | 0.78 | CETP (0.54) | CETP | |
| SCHEMBL3561125 | 0.77 | CETP (0.59) | CETPCTSA | |
| SCHEMBL3553315 | 0.77 | CETP (0.59) | CETP | |
| SCHEMBL532574 | 0.77 | CETP (0.66) | CETPNR1I2 | |
| SCHEMBL3556671 | 0.76 | CETP (0.60) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415759-A1 | CETP inhibitors | Merck Sharp & Dohme Corporation (US) | 2012-02-08 | — | — | EP | disclosed |