Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 18/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5323234 | 0.92 | PTH1R (0.67) | PTH1R | |
| SCHEMBL5330610 | 0.87 | PTH1R (0.67) | PTH1R | |
| SCHEMBL5320230 | 0.85 | PTH1R (0.65) | PTH1R | |
| SCHEMBL5329276 | 0.84 | PTH1R (0.51) | PTH1RNPC1ALDH1A1TSHRCASP1 | |
| SCHEMBL5320434 | 0.84 | PTH1R (0.51) | PTH1RNPC1ALDH1A1TSHRCASP1 | |
| SCHEMBL5321102 | 0.80 | PTH1R (0.57) | PTH1R | |
| SCHEMBL5323133 | 0.80 | PTH1R (0.57) | PTH1R | |
| SCHEMBL5326711 | 0.80 | PTH1R (0.57) | PTH1R | |
| SCHEMBL5325857 | 0.78 | PTH1R (0.66) | PTH1R | |
| SCHEMBL5326666 | 0.78 | PTH1R (0.54) | PTH1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006129120-A9 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-03-22 | — | — | WO | disclosed |
| WO-2006129120-A2 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2006-12-07 | — | — | WO | disclosed |