Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5324898 | 0.89 | F10 (0.66) | F10KCNH2KLK1 | |
| SCHEMBL5329273 | 0.88 | F10 (0.57) | F10KCNH2KLK1 | |
| SCHEMBL5320853 | 0.84 | F10 (0.65) | F10KCNH2KLK1 | |
| SCHEMBL5324672 | 0.83 | F10 (0.64) | F10KCNH2KLK1 | |
| Hydrochloric Acid SCHEMBL5322543 | 0.83 | F10 (0.63) | F10KCNH2KLK1 | |
| SCHEMBL5090987 | 0.81 | F10 (0.61) | F10KCNH2KLK1 | |
| SCHEMBL5330237 | 0.78 | GLA (0.36) | F10 | |
| SCHEMBL5088795 | 0.76 | F10 (0.63) | F10KLK1 | |
| SCHEMBL5328255 | 0.75 | F10 (0.69) | F10KCNH2KLK1 | |
| SCHEMBL5321809 | 0.75 | F10 (0.68) | F10KCNH2KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008144-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AS INHIBITORS OF FACTOR XA | ASTRAZENECA AB (SE) | 2007-01-18 | — | — | WO | disclosed |