Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23759793 | 0.83 | MAPT (0.59) | MAPTALDH1A1HTTKMT2ACYP1A2 | |
| SCHEMBL21001151 | 0.80 | MAPT (0.71) | MAPTALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL22942876 | 0.77 | HTT (0.55) | MAPTALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL23153740 | 0.77 | HTT (0.52) | MAPTALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL5327311 | 0.76 | MAPK1 (0.55) | MAPTALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL6687266 | 0.76 | MAPT (0.64) | MAPTALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL82777 | 0.76 | MAPT (0.60) | MAPTALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL21561026 | 0.75 | MAPK1 (0.57) | MAPTALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL5291433 | 0.75 | MAPT (0.54) | MAPTALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL17921471 | 0.74 | CYP1A2 (0.58) | ALDH1A1CYP1A2CYP2C19KDM4ECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135417-A1 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-11-29 | — | — | WO | disclosed |