Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 15/20 | 0.75 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | CSF1R | P07333 | 2/20 | 0.46 |
| ▸ | SYK | P43405 | 3/20 | 0.42 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5319163 | 0.89 | PDE4B (0.73) | PDE4BPDE4APDE4CPDE4DCSF1R | |
| SCHEMBL8235876 | 0.89 | PDE4B (0.57) | PDE4BCSF1R | |
| Hydrochloric Acid SCHEMBL5326547 | 0.88 | PDE4B (0.57) | PDE4BCSF1R | |
| SCHEMBL8306060 | 0.87 | PDE4B (0.70) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL1275345 | 0.86 | PDE4B (1.00) | PDE4BPDE4APDE4CPDE4DCSF1R | |
| SCHEMBL2501627 | 0.84 | PDE4B (0.63) | PDE4BPDE4APDE4CPDE4DCSF1R | |
| SCHEMBL4625955 | 0.80 | PDE4B (0.73) | PDE4BPDE4APDE4CPDE4DCSF1R | |
| SCHEMBL2480556 | 0.80 | PDE4B (0.81) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL1276128 | 0.78 | PDE4B (0.72) | PDE4BPDE4APDE4CPDE4DCSF1R | |
| SCHEMBL5322185 | 0.77 | PDE4B (0.53) | PDE4BPDE4APDE4CPDE4DCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007107499-A1 | QUINOLINE DERIVATIVES USEFUL AS PDE4 INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-09-27 | — | — | WO | disclosed |