Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 14/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2384732 | 0.91 | APP (0.36) | APPMAPTFFAR1EGLN1 | |
| SCHEMBL24409564 | 0.89 | APP (0.34) | APPMAPTFFAR1EGLN1 | |
| SCHEMBL2367316 | 0.87 | FFAR1 (0.35) | APPMAPTFFAR1EGLN1 | |
| SCHEMBL5009551 | 0.87 | FFAR1 (0.44) | APPFFAR1EGLN1FFAR4 | |
| SCHEMBL9356281 | 0.87 | FFAR1 (0.37) | APPMAPTFFAR1EGLN1 | |
| SCHEMBL13247884 | 0.86 | EGLN1 (0.48) | FFAR1EGLN1 | |
| SCHEMBL15622015 | 0.84 | CA1 (0.33) | — | |
| SCHEMBL18674481 | 0.83 | FFAR1 (0.36) | MAPTFFAR1 | |
| SCHEMBL18674465 | 0.82 | EGLN1 (0.36) | APPFFAR1EGLN1 | |
| SCHEMBL10367552 | 0.81 | ACACB (0.37) | APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007128873-A1 | A METHOD FOR THE PREPARATION OF MALEIMIDO DERIVATIVES OF BIOMOLECULE LABELING REACTANTS AND CONJUGATES DERIVED THEREOF | WALLAC OY (FI) | 2007-11-15 | — | — | WO | disclosed |
| EP-0886754-B1 | NON-COMPETITIVE IMMUNOASSAY WITH BLOCKING OF UNOCCUPIED SPECIFIC BINDING SITES ON SOLID PHASE | WALLAC OY (FI) | 2003-01-22 | — | — | EP | disclosed |
| US-6037185-A | DETERMINATION OF ANALYTES; CONTACTING SAMPLE WITH BINDING PARTNER, ADDING A BLOCKER, DISSOCIATE BLOCKER, ADD LABELLED MARKER, MEASURING SIGNAL FROM THE LABELLED MARKER BOUND TO THE BINDING PARTNER, | WALLAC OY (FI) | 2000-03-14 | — | — | US | disclosed |
| EP-0886754-A1 | NON-COMPETITIVE IMMUNOASSAY WITH BLOCKING OF UNOCCUPIED SPECIFIC BINDING SITES ON SOLID PHASE | WALLAC OY (FI) | 1998-12-30 | — | — | EP | disclosed |
| WO-1997029373-A1 | NON-COMPETITIVE IMMUNOASSAY WITH BLOCKING OF UNOCCUPIED SPECIFIC BINDING SITES ON SOLID PHASE | WALLAC OY (FI) | 1997-08-14 | — | — | WO | disclosed |
| EP-0374221-B1 | Method for enzyme activity determination characterized by the use of substrates which fluorescent properties differ from those of the converted products | KABI PHARMACIA AB (SE) | 1994-08-10 | — | — | EP | disclosed |
| US-5252462-A | Enzyme activity determinations method characterized by the using of substrates whose fluorescent properties differs those of the converted products | PHARMACIA AB (SE) | 1993-10-12 | — | — | US | disclosed |