Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3188362 | 0.82 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL3185870 | 0.78 | MEN1 (0.76) | MEN1KMT2ACYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL3185770 | 0.77 | POLB (0.74) | MEN1KMT2ACYP1A2CYP2C9POLB | |
| SCHEMBL3178935 | 0.74 | TSHR (0.77) | MEN1KMT2ACYP1A2CYP2C9POLB | |
| SCHEMBL3185894 | 0.74 | MEN1 (0.61) | MEN1KMT2ACYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL3195476 | 0.74 | MEN1 (0.61) | MEN1KMT2ACYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL3187107 | 0.74 | MEN1 (0.68) | MEN1KMT2ACYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL3189962 | 0.74 | MEN1 (0.68) | MEN1KMT2ACYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL3178853 | 0.72 | MEN1 (0.62) | MEN1KMT2ACYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL3197854 | 0.72 | POLB (0.72) | MEN1KMT2ACYP1A2CYP2C9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007115232-A2 | CXCR4 MODULATORS | CHEMOCENTRYX, INC. (US) | 2007-10-11 | — | — | WO | disclosed |