Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 10/20 | 0.47 |
| ▸ | CCKBR | P32239 | 9/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | CCKAR | P32238 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5322623 | 0.81 | PTH1R (0.51) | PTH1RCCKBR | |
| SCHEMBL5320612 | 0.80 | PTH1R (0.50) | PTH1R | |
| SCHEMBL5324138 | 0.80 | PTH1R (0.45) | PTH1RCCKBR | |
| SCHEMBL5325603 | 0.80 | PTH1R (0.48) | PTH1R | |
| SCHEMBL5325717 | 0.79 | PTH1R (0.38) | PTH1RCCKBR | |
| SCHEMBL5323921 | 0.79 | PTH1R (0.35) | PTH1RCCKBR | |
| SCHEMBL5322987 | 0.78 | PTH1R (0.42) | PTH1R | |
| SCHEMBL5323824 | 0.78 | PTH1R (0.49) | PTH1R | |
| SCHEMBL5320208 | 0.78 | PTH1R (0.52) | PTH1RCCKBR | |
| SCHEMBL5325682 | 0.78 | PTH1R (0.52) | PTH1RCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006129120-A9 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-03-22 | — | — | WO | disclosed |
| WO-2006129120-A2 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2006-12-07 | — | — | WO | disclosed |