Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 5/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | DRD4 | P21917 | 3/20 | 0.51 |
| ▸ | DRD3 | P35462 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5322682 | 0.83 | GRM2 (0.56) | GRM2DRD2DRD4DRD3LMNA | |
| SCHEMBL5322728 | 0.80 | GRM2 (0.51) | GRM2DRD2DRD4DRD3LMNA | |
| SCHEMBL5321874 | 0.80 | GRM2 (0.55) | GRM2DRD2DRD4DRD3SMN1; SMN2 | |
| SCHEMBL5327996 | 0.80 | GRM2 (0.55) | GRM2DRD2DRD4DRD3SMN1; SMN2 | |
| SCHEMBL5324285 | 0.80 | GRM2 (0.55) | GRM2DRD2DRD4DRD3SMN1; SMN2 | |
| SCHEMBL5328000 | 0.80 | GRM2 (0.55) | GRM2DRD2DRD4DRD3SMN1; SMN2 | |
| SCHEMBL5325773 | 0.80 | GRM2 (0.55) | GRM2DRD2DRD4DRD3SMN1; SMN2 | |
| SCHEMBL5326833 | 0.77 | GRM2 (0.57) | GRM2DRD2DRD4DRD3SMN1; SMN2 | |
| SCHEMBL5325461 | 0.77 | GRM2 (0.57) | GRM2DRD2DRD4DRD3SMN1; SMN2 | |
| SCHEMBL5325322 | 0.77 | GRM2 (0.57) | GRM2DRD2DRD4DRD3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135527-A2 | BENZIMIDAZOLYL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | disclosed |