Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 6/20 | 0.53 |
| ▸ | TNF | P01375 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.44 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.44 |
| ▸ | MDM4 | O15151 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30844644 | 0.89 | HDAC1 (0.52) | TLR2TNFHDAC1HDAC2MDM4 | |
| SCHEMBL23811028 | 0.88 | TLR2 (0.52) | TLR2TNFHDAC1HDAC2MDM4 | |
| SCHEMBL30844620 | 0.88 | TLR2 (0.52) | TLR2TNFHDAC1HDAC2MDM4 | |
| SCHEMBL30861891 | 0.85 | TNF (0.59) | TLR2TNFHDAC1HDAC2MDM4 | |
| SCHEMBL3366333 | 0.85 | TNF (0.59) | TLR2TNFHDAC1HDAC2MDM4 | |
| SCHEMBL29401900 | 0.85 | TNF (0.59) | TLR2TNFHDAC1HDAC2MDM4 | |
| SCHEMBL31186620 | 0.85 | TNF (0.59) | TLR2TNFHDAC1HDAC2MDM4 | |
| SCHEMBL120685 | 0.85 | TNF (0.59) | TLR2TNFHDAC1HDAC2MDM4 | |
| SCHEMBL29398946 | 0.85 | TNF (0.59) | TLR2TNFHDAC1HDAC2MDM4 | |
| SCHEMBL2589116 | 0.85 | TNF (0.59) | TLR2TNFHDAC1HDAC2MDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007109615-A2 | β -LACTAMYL VASOPRESSIN V2 ANTAGONISTS | AZEVAN PHARMACEUTICALS, INC. (US) | 2007-09-27 | — | — | WO | disclosed |